378. Clinical study of PIVKA-II

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Impact of PIVKA-II in diagnosis of hepatocellular carcinoma

Liver cancer grows silently with mild or no symptoms until advanced. In the absence of an effective treatment for advanced stage of hepatic cancer hope lies in early detection, and screening for high-risk population. Among Egyptians viral hepatitis is the most common risk factor for hepatocellular carcinoma (HCC). The current work was designed to determine the level of prothrombin induced by vi...

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Increased PIVKA-II concentrations in patients with cystic fibrosis.

Serum vitamin K concentrations and prothrombin induced by absence of vitamin K (PIVK-II) concentrations were assayed in 43 patients with cystic fibrosis. Twenty nine showed a normal PIVKA-II and vitamin K concentrations; 14 showed an increased PIVKA-II concentration, in one of whom serum vitamin K was decreased. Although their vitamin K concentrations were normal, some patients with cystic fibr...

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PIVKA-II concentrations in patients with cystic fibrosis.

Montalembert et al report that PIVKA-II was detected in 33% of patients with cystic fibrosis, while vitamin K, plasma concentrations were normal.' It is astonishing that despite daily supplements of 5-10 mg vitamin K,, PIVKA-II was detectable in these patients. The authors conclude that PIVKAII is not associated with vitamin K deficiency, but with the use of antibiotics. There is some doubt as ...

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Clinical Significance of AFP and PIVKA-II Responses for Monitoring Treatment Outcomes and Predicting Prognosis in Patients with Hepatocellular Carcinoma

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ژورنال

عنوان ژورنال: Japanese Journal of Radiological Technology

سال: 1990

ISSN: 0369-4305,1881-4883

DOI: 10.6009/jjrt.kj00003322500